DMPK

Pharmacokinetics


  • PK in rat and mouse (normal & tumor bearing animals) for IND and NDA submissions
  • Rapid Pilot PK study for early preclinical support.
  • Dose proportionality and gender effect studies
  • Route of administration oral, i.v (bolus, infusion), i.p, topical.
  • Tissue distribution studies
  • Excretion studies
  • Bioavailibility studies
  • Statistical analysis of PK data using WinNonLin