Nowadays, unorganized, and stressful lifestyle causes various health problems. One of these is a change in mental and behavioral health. Neuropharmacology is a branch of science deals with mental (Stress, Depression, Anxiety, Dementia) and behavioral health (Alzheimer, Parkinson, Schizophrenia). For researchers and physicians, this will be a challenging area of the medical field in the succeeding decades due to its complexity.

Dabur Research Foundation having a well-equipped neuropharmacology facility with advanced technology. The neuropharmacology facility consists of various apparatus and instruments connected digitally with the software/camera and record data instantaneously such as…

  • Morris water maze for learning and memory.
  • Elevated plus maze for anxiety.
  • Y maze for spontaneous memory.
  • Open field apparatus for locomotor activity, anxiety, and willingness to explore.
  • Rotarod for motor coordination and muscle strength.
  • Actophotometer for mobility/locomotion/bradykinesia.
  • Passive avoidance for learning and memory.
  • Pole test for motor coordination.
  • Traction test for motor coordination.
  • Grip strength meter for muscle grip.
  • Hole poke for Neophobic behavior.
  • Stereotaxic for CSF collection and injection into brain.
  • Tail flick for analgesic response.
  • Hot and cold plate for pain response.
  • Von Frey for mechanical allodynia.
  • Pressure application measurement (PAM) for mechanical sensitivity.
  • Balance beam for motor coordination.
  • Grid test apparatus for motor coordination.

Many animal models in neuropharmacology have been validated with appropriate study design to accomplish the desired objectives such as…

  • Vincristine-induced peripheral neuropathy in rats.
  • MPTP induced model of Parkinson’s disease in mice.
  • Scopolamine induced dementia model in rats/mice.
  • Streptozotocin (Intracerebroventricular) induced dementia model in rats/mice.
  • Anti-anxiety activity using Elevated Plus Maze Test in rats/mice.
  • Anti-depressant activity using Force swim test in rats.
  • Anti-depressant activity using tail suspension test in rats/mice.
  • Muscle relaxant activity using Rota rod test in rats/mice.
  • Learning & memory potential using Morris water maze test in rats.
  • Anti-stress activity using Unpredictable Chronic Stress (UCS) model in rats.
  • Learning & memory potential using Y Maze test in rats.
  • Streptozotocin induced neuropathic pain in rats.
  • D-Gal induced ageing in rats.