Anti-Nociceptive activity in the CCI-peripheral neuropathy Rat Model |
Gabapentin |
Pain sensitivity by Pressure application, % Activity |
Chemotherapy Vincristine-induced Peripheral Neuropathy (CIPN) in Rats |
Gabapentin |
Pain sensitivity by Pressure application, % Activity, Cytokine estimation |
MPTP induced model of Parkinson’s disease in Mice |
L-DOPA |
Pole Test, Traction Test, Dopamine level in brain , Brain Histology |
Anti-dementia activity using Scopolamine induced rat/mice model |
Donepzil Hydrocloride |
Body weight, Passive Avoidance Test, Acetylcholinestrase, Neural growth factor, TNF -alpha estimation and Histopathology of Brain |
Anti-dementia activity using STZ (Intracerebroventricular) induced rat/mice model |
Donepzil Hydrocloride |
Body weight, Morris Water Maze Test , Y Maze and Histopathology of Brain |
Anti-anxeity activity using Elevated Plus Maze Test using Rat & Mice |
Diazepam |
Time spent in open & close arm to analyse Anxiety |
Anti-depressant activity using Force swim test in Rats |
Imipramine |
Body weight, Feed intake, Actimeter, Force swim Test, Open field Test, Adrenal weight, Corticosterone estimation. |
Anti-depressant activity using tail suspension test using Rat & Mice |
Imipramine |
Body weight, Feed intake, Actimeter, Elevated Plus maze, Open field Test, Corticosterone estimation. |
Muscle relaxant activity using rota rod test in rat & Micel |
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RPM-Time of Fall from Rotarod in Sec. |
Learning & memory potential using Morris water maze test in Rats |
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Time spent in NEWS zones and Time to reach hidden platform in water maze (MWM), Acetlycholine and Dopamine levele estimation to analyse memory |
Anti-stress activivty using Unpredicatable Chronic Stress (UCS) Model in Rats |
Imipramine |
Body weight, Feed intake, Actimeter, Elevated Plus maze, Open field Test, Adrenal weight and Corticosterone, Serotonin, Anti-oxidant level estimation. |
Learning & memory potential using Y Maze test |
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Time spent in Center and XYZ zone, Acetlycholine and Dopamine levele estimation to analyse Leaning and Memory potential. |