Subcutaneous Xenograft models using athymic Nude and SCID Mice |
Cytotoxic Agents |
Tumor Volume, Growth Inhibition, %T/C, Growth Delay, Body weight |
Syngenic tumour models using BALB/c and C57BL6 Mice |
Cytotoxic Agents |
Tumor Volume, Growth Inhibition, %T/C, Growth Delay, Body weight |
Surgical Orthotopic models using Nude and SCID Mice |
Cytotoxic Agents |
Survival proportion, Body weight, Histology, Clinical sign |
Matrigel Plug Assay for In-vivo Angiogenesis |
Cytotoxic Agents |
Hemoglobin content, Histology, IHC |
In-vivo Anti-Metastasis assay using B16F10 Intravenous models |
Cytotoxic Agents |
Lung melanoma colony count, Body weight , clinical sign, Histology |
In-vivo anti-Leukemia activity using NOD SCID mice model |
Cytotoxic Agents |
Clinical score, Body weight change, % Increased Life span, Kaplan Meier curve, CD 45 level in whole blood |
Tumorigenesis assay using using athymic Nude and SCID Mice |
Cytotoxic Agents |
Tumor Volume, Growth rate, % take up , Tumor volume doubling time |
AOM-DSS induced colon cancer in C57BL6 Mice |
Cytotoxic Agents |
Body weight, clinical sign,Polyps count, Cytokine estimation, Histology, IHC |
DMBA+ Croton Oil induced skin cancer model in mice |
Cytotoxic Agents |
Body weight, Polyps count, & Histology |