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Tissue Distribution Studies

INTRODUCTION A comprehensive knowledge of the absorption, distribution, metabolism and elimination of a compound is important for the interpretation of pharmacology and toxicology studies. Tissue distribution studies are essential in…
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Regulatory Toxicology

'All substances are poisons; there is none which is not a poison. The right dose differentiates a poison'- Paracelsus Anciently toxicology was known as the ‘Science of Poison,’ now a…
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Probiotics, Prebiotics, and the Microbiome

Numerous of microbes inhabit the human body, collectively forming the human microbiota. These microbes create complex, organ-specific and adaptive ecosystems, which continually impact the host’s physiology. The bacteria that colonize,…
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Intrathecal Pharmacokinetics

The Intrathecal delivery of compounds acting on central nervous system (CNS) has enhanced interest due to the absence of continuous barriers between the cerebrospinal fluid (CSF) and CNS, which makes…
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